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Alpha-Lipoic Acid vs. R-Lipoic Acid

Filed Under: Health Concerns & Ailments,Supplements at 11:00 am | By: Mauricio Matusiak, Senior Editor
vsWhat is the difference between alpha-lipoic acid and R-lipoic acid? Let’s break down this subject with a quick overview of this important antioxidant.

Alpha-lipoic acid is an antioxidant that is made by the body and is found in every cell. It helps turn glucose into energy. Antioxidants attack free radicals, which may cause harmful chemical reactions that can damage cells in the body, making it harder for the body to fight off infections. Studies have shown that alpha-lipoic acid may help regenerate antioxidants and make them active again.

Alpha-lipoic acid exists in three different forms: alpha R-lipoic acid, alpha S-lipoic acid, and alpha RS-lipoic acid. Alpha S-lipoic acid and alpha RS-lipoic acid are synthetics created by chemical synthesis, and commonly known and sold as alpha-lipoic acid supplements. Alpha lipoic acid is referred to as racemic molecule, which contains both the natural and the unnatural form (cis and trans respectively).

On the other hand, alpha R-lipoic acid is the natural form of lipoic acid and the only version that exists in nature, is produced in the body, and synthesized by both plants and animals. R-lipoic acid contains only the natural form (cis) form of ALA.

Considered an ideal antioxidant, Lipoic Acid is a super-antioxidant that does everything an antioxidants should do and a little more. Some antioxidants work only in water such as vitamin C or vitamin E, but alpha-lipoic acid is both fat and water soluble, as it can work throughout the body. Both versions of lipoic acid have a very short life in the human body and it’s highly recommended that you take a sustained release version of ALA.

More Related Products

NOW Foods – Alpha Lipoic Acid 600 mg. – 60 Vegetarian Capsules




3 Responses to “Alpha-Lipoic Acid vs. R-Lipoic Acid”

  1. Joe Pastoriza says:

    I would like to know if R-lipoic Acid has any effect on cholesterol or heart disease and if it is helpful for neuropathy by itself. Thank you.

  2. Diane m says:

    All antioxidants help prevent oxidation and free radicals. Free radicals cause inflammation of the heart and throughout the body. Inflammation encourqges calcification of the arteries. Oxidation of cholesterol is also a problem.

  3. Jim says:

    When taking ALA don’t over do it. You might break out in itchy rash. I am talking 1000 MG BID.Your urine will smell to high heaven also.

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